Tropical Spastic Paraplegia

《英文msh詞典》Tropical Spastic Paraplegia
[入口詞] Tropical Spastic Paraplegia
[主題詞] Paraparesis,Tropical Spastic
[英文釋義] A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean,Colombia,India,and Africa,as well as in the southwestern region of Japan; associated with infection by human T-cell leukemia virus type I (HUMAN T-LYMPHOTROPIC VIRUS 1). Clinical manifestations include a slowly progressive spastic weakness of the legs,increased reflexes,Babinski signs,incontinence,and loss of vibratory and position sensation. On pathologic examination inflammatory,demyelination,and necrotic lesions may be found in the spinal cord. (Adams et al.,Principles of Neurology,6th ed,p1239)